Steffen Thiel Selected Research

Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)

1/2020	Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.
11/2016	Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing.
1/2016	Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study.
1/2014	Lectin pathway of complement activation and relation with clinical complications in critically ill children.
3/2005	Preoperative mannan-binding lectin pathway and prognosis in colorectal cancer.

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Steffen Thiel Research Topics

Disease

30	Infections 01/2021 - 01/2003
17	Inflammation (Inflammations) 01/2021 - 07/2002
10	Neoplasms (Cancer) 01/2020 - 05/2011
10	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2017 - 10/2003
7	Diabetic Nephropathies (Diabetic Nephropathy) 01/2017 - 06/2004
6	Type 2 Diabetes Mellitus (MODY) 01/2021 - 10/2006
6	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 06/2015
6	Rheumatoid Arthritis 11/2020 - 12/2013
6	Arthritis (Polyarthritis) 01/2020 - 07/2009
6	Mannose-Binding Protein Deficiency 04/2016 - 10/2005
5	Reperfusion Injury 01/2020 - 01/2003
4	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 01/2003
4	Sepsis (Septicemia) 12/2020 - 07/2007
4	Critical Illness (Critically Ill) 01/2016 - 03/2003
4	Colorectal Neoplasms (Colorectal Cancer) 01/2015 - 02/2005
3	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2022 - 07/2015
3	Macular Degeneration (Age-Related Maculopathy) 12/2020 - 06/2011
3	Out-of-Hospital Cardiac Arrest 11/2020 - 04/2016
3	Hemolysis 10/2020 - 01/2018
3	Leprosy (Hansen's Disease) 01/2020 - 01/2013
3	Multiple Myeloma 01/2019 - 07/2006
3	Necrosis 01/2018 - 06/2011
3	Multiple Sclerosis 08/2012 - 02/2007
3	Acute-Phase Reaction 09/2010 - 03/2003
2	Common Variable Immunodeficiency 09/2022 - 10/2019
2	COVID-19 01/2021 - 01/2021
2	Choroidal Neovascularization 12/2020 - 05/2013
2	Coma (Comas) 11/2020 - 04/2016
2	Heart Arrest (Cardiac Arrest) 11/2020 - 06/2018
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2020 - 10/2017
2	Neutropenia 01/2019 - 05/2011
2	Lymphoma (Lymphomas) 01/2019 - 01/2018
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 01/2018
2	Crohn Disease (Crohn's Disease) 05/2017 - 06/2014
2	Ischemia 04/2016 - 10/2006
2	Myocardial Infarction 03/2014 - 04/2012
2	HIV Infections (HIV Infection) 01/2013 - 07/2008
2	Burns 06/2007 - 02/2006
2	Diabetic Angiopathies (Diabetic Angiopathy) 10/2006 - 11/2005
1	Alzheimer Disease (Alzheimer's Disease) 08/2021
1	Synucleinopathies 08/2021
1	Parkinson Disease (Parkinson's Disease) 08/2021
1	Multiple System Atrophy 08/2021
1	Dementia (Dementias) 08/2021
1	Kidney Diseases (Kidney Disease) 08/2021
1	Membranous Glomerulonephritis (Membranous Nephropathy) 08/2021
1	Lupus Nephritis 08/2021
1	Acute Coronary Syndrome 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Pneumococcal Infections 01/2021
1	Chronic Renal Insufficiency 01/2021
1	Post-Cardiac Arrest Syndrome 11/2020

Drug/Important Bio-Agent (IBA)

50	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2021 - 07/2002
45	Complement System Proteins (Complement)IBA 08/2021 - 11/2005
34	LectinsIBA 01/2021 - 11/2003
27	Proteins (Proteins, Gene)FDA Link 09/2022 - 01/2003
15	FicolinsIBA 01/2022 - 08/2009
10	Serine Proteases (Serine Protease)IBA 01/2020 - 01/2003
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2005
5	C-Reactive ProteinIBA 01/2021 - 03/2005
5	AntibodiesIBA 01/2021 - 02/2007
5	CollagenIBA 01/2020 - 07/2009
5	Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)IBA 01/2020 - 03/2005
4	CytokinesIBA 01/2020 - 11/2005
4	Serine (L-Serine)FDA Link 09/2018 - 07/2008
3	complement C3d,gIBA 11/2020 - 01/2018
3	AntigensIBA 01/2020 - 01/2003
3	Collectins (Collectin)IBA 01/2020 - 01/2015
3	Insulin (Novolin)FDA Link 01/2017 - 03/2003
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2014
2	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2018
2	Immunoglobulin G (IgG)IBA 12/2020 - 01/2020
2	Immunoglobulin M (IgM)IBA 01/2020 - 10/2006
2	Complement Factor D (Factor D)IBA 01/2020 - 11/2016
2	Biological ProductsIBA 01/2018 - 02/2006
2	CarbohydratesIBA 10/2015 - 02/2012
2	Complement Inactivating AgentsIBA 09/2014 - 03/2014
2	EpitopesIBA 01/2014 - 10/2010
2	Lactalbumin (alpha-Lactalbumin)IBA 04/2013 - 06/2011
2	Interferon-betaIBA 08/2012 - 10/2009
2	Streptozocin (Streptozotocin)FDA Link 01/2012 - 01/2011
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2007 - 11/2005
1	SynucleinsIBA 08/2021
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2021
1	Sitagliptin Phosphate (Januvia)FDA Link 01/2021
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2021
1	inter-alpha-inhibitorIBA 01/2021
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2021
1	Pregnancy-Associated alpha 2-Macroglobulins (alpha 2 Macroglobulin)IBA 01/2021
1	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	AntithrombinsIBA 01/2021
1	Classical Pathway Complement C5 ConvertaseIBA 10/2020
1	Complement C3b (C3bi)IBA 01/2020

Therapy/Procedure

10	Therapeutics 01/2018 - 03/2003
4	Transplantation 01/2019 - 12/2008
4	Drug Therapy (Chemotherapy) 01/2019 - 07/2006
2	Hematopoietic Stem Cell Transplantation 01/2019 - 01/2018
2	Critical Care (Surgical Intensive Care) 03/2016 - 01/2016
1	Induced Hypothermia 11/2020